← Back to the blog 💊 Mind & Medicine

Starting an Antidepressant? Here's What No One Tells You

The pharmacology and the feelings of starting a new medication are two different conversations — most people only get one of them.

Starting an antidepressant is a significant decision, and most people are given the pharmacology — dosage, timing, side effects — but not much space for the feelings that come with it. Having stood on the other side of the pharmacy counter for many years, and now sitting in a counselling room, I've seen both halves of this conversation, and they matter equally.

The first thing worth knowing: it is normal to feel worse before you feel better, or to feel nothing for a few weeks while your body adjusts. Most antidepressants take two to six weeks to show their full effect, and the early days can bring side effects — nausea, sleep changes, a strange flatness — before the benefit arrives. This is not a sign that it isn't working. It's usually a sign that it's still settling in.

The second thing worth knowing: there is often an emotional layer underneath the decision itself, separate from the medication's effects. Some people feel relief. Others feel a quiet grief, or a sense of failure, as though needing medication means something about their willpower or character. It doesn't. Depression and anxiety are not failures of effort, and treating them with medication is not a shortcut — it's medical care, the same as treating any other condition your body is struggling with.

The third thing, and the one I most want people to hear: you are allowed to ask questions, and you are allowed to feel two things at once — hope and hesitation, relief and grief, willingness and fear. None of that needs to be resolved before you start.

Counselling alongside medication isn't about replacing what your prescriber is doing. It's about having a space to work through everything the prescription doesn't cover — the feelings about starting, the adjustment period, the questions you didn't think to ask in a fifteen-minute appointment. Always speak to your prescriber about the medical side. But you don't have to carry the emotional side of it alone.

If this resonated, Nisha offers a free 15-minute introduction call — no obligation.

Book a Free Introduction Call